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Brief Report for CytoDyn Inc. (OTCQB: CYDY)
CytoDyn is a biotechnology company focused on the clinical development and potential commercialization of humanized monoclonal antibodies for the treatment and prevention of Human Immunodeficiency Virus (HIV) infection. CytoDyn has one of the leading monoclonal antibodies under development for HIV infection, PRO 140, which has finished Phase 2 clinical trials with demonstrated antiviral activity in man and is currently in Phase 3. PRO 140 blocks the HIV co-receptor CCR5 on T-cells which prevents viral entry. Clinical trial results thus far indicate that PRO 140 does not negatively affect the normal immune functions that are mediated by CCR5. Results from six Phase 1 and Phase 2 human clinical trials have shown that PRO 140 can significantly reduce viral burden in people infected with HIV. A recent Phase 2b clinical trial demonstrated that PRO 140 can prevent viral escape in patients during several weeks of interruption from conventional drug therapy. CytoDyn intends to continue to develop PRO 140 as a therapeutic anti-viral agent in persons infected with HIV and to pursue non-HIV indications where CCR5 and its ligand CCL5 may be involved.
February 23, 2016. In the following press release the company announced that it submitted a Phase 3 protocol for a monotherapy trial, along with the Topline Report for its Phase 2b monotherapy trial to the U.S. Food and Drug Administration (FDA). http://www.otcmarkets.com/stock/CYDY/news/CytoDyn-Initiates-Phase-3-Monotherapy-Trial-for-HIV-Patients?id=125872&b=y
January 28, 2016. This is a company press release that reports on Full Virologic Suppression in Eleven HIV Patients on PRO 140 Monotherapy for Up to 17 Months http://www.otcmarkets.com/stock/CYDY/news/CytoDyn-Reports-Full-Virologic-Suppression-in-Eleven-HIV-Patients-on-PRO-140-Monotherapy-for-Up-to-17-Months?id=124048&b=y
February 23, 2016. The company issues this PROXY STATEMENT SPECIAL MEETING OF STOCKHOLDERS. The shareholders’ meeting is scheduled for March 18, 2016. http://www.otcmarkets.com/edgar/GetFilingHtml?FilingID=11192485
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